Huperzine A Ameliorates Cognitive Deficits in Streptozotocin-Induced Diabetic Rats

Huperzine A Ameliorates Cognitive Deficits in Streptozotocin-Induced Diabetic Rats

The present study was designed to probe the effects of Huperzine A (HupA) on diabetes-associated cognitive decline (DACD) using a streptozotocin (STZ)-injected rat model. Diabetic rats were treated with HupA (0.05 and 0.1 mg/kg) for seven weeks. Memory functions were evaluated by the water maze test...

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Bibliographic Details
Main Authors: Xiao-Yuan Mao, Dan-Feng Cao, Xi Li, Ji-Ye Yin, Zhi-Bin Wang, Ying Zhang, Chen-Xue Mao, Hong-Hao Zhou, Zhao-Qian Liu
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:International Journal of Molecular Sciences
Subjects:
huperzine A
diabetes-associated cognitive decline
brain-derived neurotrophic factor
oxidative stress
inflammation
apoptosis
Online Access:http://www.mdpi.com/1422-0067/15/5/7667

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http://www.mdpi.com/1422-0067/15/5/7667

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