Syntaxin-17-Dependent Mitochondrial Dynamics is Essential for Protection Against Oxidative-Stress-Induced Apoptosis

In this study, cell death induced by the oxidant tert-butylhydroperoxide (tBH) was observed in U<sub>2</sub>OS cells; this phenotype was rescued by Syntaxin 17 (STX17) knockout (KO) but the mechanism is unknown. STX17 plays dual roles in autophagosome&#8722;lysosome fusion and mitoch...

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Bibliographic Details
Main Authors: Binran Wang, Xiaoyue Xiao, Fanwei Huang, Rong Liu
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Antioxidants
Subjects:
ros
Online Access:https://www.mdpi.com/2076-3921/8/11/522