Decidualized endometrial stromal cells present with altered androgen response in PCOS

Decidualized endometrial stromal cells present with altered androgen response in PCOS

Abstract Hyperandrogenic women with PCOS show disrupted decidualization (DE) and placentation. Dihydrotestosterone (DHT) is reported to enhance DE in non-PCOS endometrial stromal cells (eSCCtrl); however, this has not been assessed in PCOS cells (eSCPCOS). Therefore, we studied the transcriptome pro...

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Bibliographic Details
Main Authors: Masuma Khatun, Alvin Meltsov, Darja Lavogina, Marina Loid, Keiu Kask, Riikka K. Arffman, Henna-Riikka Rossi, Freddy Lättekivi, Kersti Jääger, Kaarel Krjutškov, Ago Rinken, Andres Salumets, Terhi T. Piltonen
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95705-0

Internet

https://doi.org/10.1038/s41598-021-95705-0

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