Matrix-immobilized BMP-2 on microcontact printed fibronectin as in vitro tool to study BMP-mediated signaling and cell migration

Matrix-immobilized BMP-2 on microcontact printed fibronectin as in vitro tool to study BMP-mediated signaling and cell migration

During development, bone morphogenetic proteins (BMPs) exert important functions in several tissues by regulating signaling for cell differentiation and migration. In vivo the extracellular matrix (ECM) not only provides a support for adherent cells, but also presents a reservoir of growth factors (...

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Bibliographic Details
Main Authors: Kristin eHauff, Chiara eZambarda, Miriam eDietrich, Maria eHalbig, Anna Luise Grab, Rebecca eMedda, Elisabetta Ada eCavalcanti-Adam
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Fibronectins
BMP-2
C2C12 myoblasts
microcontact printing
Bmp/Smad signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00062/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00062/full

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