Upregulated UHRF1 promotes bladder cancer cell invasion by epigenetic silencing of KiSS1.

Upregulated UHRF1 promotes bladder cancer cell invasion by epigenetic silencing of KiSS1.

Ubiquitin-like with PHD and RING finger domains 1 (UHRF1), as an epigenetic regulator, plays important roles in the tumorigenesis and cancer progression. KiSS1 functions as a metastasis suppressor in various cancers, and epigenetic silencing of KiSS1 increases the metastatic potential of cancer cell...

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Bibliographic Details
Main Authors: Yu Zhang, Zhen Huang, Zhiqiang Zhu, Xin Zheng, Jianwei Liu, Zhiyou Han, Xuetao Ma, Yuhai Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182677?pdf=render

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http://europepmc.org/articles/PMC4182677?pdf=render

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