Streptavidin cooperative allosterism upon binding biotin observed by differential changes in intrinsic fluorescence

While the binding of biotin by streptavidin does not appear to be cooperative in the traditional sense of altered binding strength, it has been suggested that it may be cooperative in terms of differential structural changes in the protein. In this work we present intrinsic tryptophan fluorescence d...

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Bibliographic Details
Main Authors: Mark J. Waner, James M. Hiznay, Anthony T. Mustovich, William Patton, Charles Ponyik, David P. Mascotti
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S240558081830181X