Prioritizing candidate disease metabolites based on global functional relationships between metabolites in the context of metabolic pathways.

Identification of key metabolites for complex diseases is a challenging task in today's medicine and biology. A special disease is usually caused by the alteration of a series of functional related metabolites having a global influence on the metabolic network. Moreover, the metabolites in the...

Full description

Bibliographic Details
Main Authors: Desi Shang, Chunquan Li, Qianlan Yao, Haixiu Yang, Yanjun Xu, Junwei Han, Jing Li, Fei Su, Yunpeng Zhang, Chunlong Zhang, Dongguo Li, Xia Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4143229?pdf=render