The role of the electrokinetic charge of neurotrophis-based nanocarriers: protein distribution, toxicity, and oxidative stress in in vitro setting

Abstract Background The rational chemical design of nanoparticles can be readily controlled and optimized by quantitatively studying protein adsorption at variously charged polymer carriers, determining their fate in biological fluids. We manufactured brain-derived neurotrophic factor (BDNF) -based...

Full description

Bibliographic Details
Main Authors: Maria Dąbkowska, Zofia Ulańczyk, Karolina Łuczkowska, Dorota Rogińska, Anna Sobuś, Monika Wasilewska, Maria Olszewska, Katarzyna Jakubowska, Bogusław Machaliński
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Nanobiotechnology
Online Access:https://doi.org/10.1186/s12951-021-00984-4