Short- and long-term effects of LRRK2 on axon and dendrite growth.

Mutations in leucine-rich repeat kinase 2 (LRRK2) underlie an autosomal-dominant form of Parkinson's disease (PD) that is clinically indistinguishable from idiopathic PD. The function of LRRK2 is not well understood, but it has become widely accepted that LRRK2 levels or its kinase activity, wh...

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Bibliographic Details
Main Authors: Bryan Sepulveda, Roxana Mesias, Xianting Li, Zhenyu Yue, Deanna L Benson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3640004?pdf=render