Genome-wide Functional Analysis Reveals Factors Needed at the Transition Steps of Induced Reprogramming

Although transcriptome analysis can uncover the molecular changes that occur during induced reprogramming, the functional requirements for a given factor during stepwise cell-fate transitions are left unclear. Here, we used a genome-wide RNAi screen and performed integrated transcriptome analysis to...

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Bibliographic Details
Main Authors: Chao-Shun Yang, Kung-Yen Chang, Tariq M. Rana
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471400566X