ppargc1a controls nephron segmentation during zebrafish embryonic kidney ontogeny

Nephron segmentation involves a concert of genetic and molecular signals that are not fully understood. Through a chemical screen, we discovered that alteration of peroxisome proliferator-activated receptor (PPAR) signaling disrupts nephron segmentation in the zebrafish embryonic kidney (Poureetezad...

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Bibliographic Details
Main Authors: Joseph M Chambers, Shahram Jevin Poureetezadi, Amanda Addiego, Manuela Lahne, Rebecca A Wingert
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/40266