Clinical Outcome in Pediatric Patients with Philadelphia Chromosome Positive ALL Treated with Tyrosine Kinase Inhibitors Plus Chemotherapy—The Experience of a Polish Pediatric Leukemia and Lymphoma Study Group

Clinical Outcome in Pediatric Patients with Philadelphia Chromosome Positive ALL Treated with Tyrosine Kinase Inhibitors Plus Chemotherapy—The Experience of a Polish Pediatric Leukemia and Lymphoma Study Group

The treatment of children with Philadelphia chromosome positive acute lymphoblastic leukemia (ALL Ph+) is currently unsuccessful. The use of tyrosine kinase inhibitors (TKIs) combined with chemotherapy has modernized ALL Ph+ therapy and appears to improve clinical outcome. We report herein the toxic...

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Bibliographic Details
Main Authors: Joanna Zawitkowska, Monika Lejman, Marcin Płonowski, Joanna Bulsa, Tomasz Szczepański, Michał Romiszewski, Agnieszka Mizia-Malarz, Katarzyna Derwich, Grażyna Karolczyk, Tomasz Ociepa, Magdalena Ćwiklińska, Joanna Trelińska, Joanna Owoc-Lempach, Ninela Irga-Jaworska, Anna Małecka, Katarzyna Machnik, Justyna Urbańska-Rakus, Radosław Chaber, Jerzy Kowalczyk, Wojciech Młynarski
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
ALL Ph+
children
tyrosine kinase inhibitors (TKIs)
toxicity
outcome
Online Access:https://www.mdpi.com/2072-6694/12/12/3751

Internet

https://www.mdpi.com/2072-6694/12/12/3751

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