Treating Intracranial Abscesses in Rats with Stereotactic Injection of Biodegradable Vancomycin-Embedded Microparticles

Brain abscesses are emergent and life-threating despite advances in modern neurosurgical techniques and antibiotics. The present study explores the efficacy of vancomycin embedded to 50:50 poly(lactic-<i>co</i>-glycolide acid) (PLGA) microparticles in the treatment of brain abscess. The...

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Bibliographic Details
Main Authors: Yuan-Yun Tseng, Ching-Wei Kao, Kuo-Sheng Liu, Ya-Ling Tang, Yen-Wei Liu, Shih-Jung Liu
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/2/91