Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives.

Inhibition of angiogenesis is a promising addition to current cancer treatment strategies. Neutralization of vascular endothelial growth factor by monoclonal antibodies is clinically effective but may cause side effects due to thrombosis. Low molecular weight angiogenesis inhibitors are currently le...

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Bibliographic Details
Main Authors: Anders N Hansen, Christine D Bendiksen, Lene Sylvest, Tina Friis, Dan Staerk, Flemming Steen Jørgensen, Christian A Olsen, Gunnar Houen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0045405