Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets
Dentate neural stem cells produce neurons throughout life in mammals. Sonic hedgehog (Shh) is critical for maintenance of these cells; however, the perinatal source of Shh is enigmatic. In the present study, we examined the role of Shh expressed by hair follicles (HFs) that expand perinatally in tem...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/07834 |