Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis.

Organ dysfunction is a major concern in sepsis pathophysiology and contributes to its high mortality rate. Neutrophil extracellular traps (NETs) have been implicated in endothelial damage and take part in the pathogenesis of organ dysfunction in several conditions. NETs also have an important role i...

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Main Authors: Paula Giselle Czaikoski, José Maurício Segundo Correia Mota, Daniele Carvalho Nascimento, Fabiane Sônego, Fernanda Vargas e Silva Castanheira, Paulo Henrique Melo, Gabriela Trentin Scortegagna, Rangel Leal Silva, Romualdo Barroso-Sousa, Fabrício Oliveira Souto, Antonio Pazin-Filho, Florencio Figueiredo, José Carlos Alves-Filho, Fernando Queiróz Cunha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4743982?pdf=render