Quantitative analysis of ligand-EGFR interactions: a platform for screening targeting molecules.

Epidermal growth factor receptor (EGFR) is often constitutively stimulated in many cancers owing to the binding of ligands such as epidermal growth factor (EGF). Therefore, it is necessary to investigate the interaction between EGFR and its targeting biomolecules. The main aim of this study was to e...

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Bibliographic Details
Main Authors: Wei-Ting Kuo, Wen-Chun Lin, Kai-Chun Chang, Jian-Yuan Huang, Ko-Chung Yen, In-Chi Young, Yu-Jun Sun, Feng-Huei Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4344348?pdf=render