8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage.

Ten years on from the finishing of the human reference genome sequence, it remains unclear what fraction of the human genome confers function, where this sequence resides, and how much is shared with other mammalian species. When addressing these questions, functional sequence has often been equated...

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Bibliographic Details
Main Authors: Chris M Rands, Stephen Meader, Chris P Ponting, Gerton Lunter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25057982/pdf/?tool=EBI