Endothelial dysfunction as a nexus for endothelial cell-cardiomyocyte miscommunication

Most studies of the heart focus on cardiomyocytes (CM) at the exclusion of other cell types such as myocardial endothelial cells (EC). Such mono-cellular approaches propagate the presumption that EC provide a mere passive lining or supportive role. In fact, EC contribute to a dynamic network regulat...

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Bibliographic Details
Main Authors: Thorsten M. Leucker, Steven P. Jones
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00328/full