Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction.

Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction.

Beta cell dysfunction accompanies and drives the progression of type 2 diabetes mellitus (T2D), but there are few clinical biomarkers available to assess islet cell stress in humans. Secretagogin, a protein enriched in pancreatic islets, demonstrates protective effects on beta cell function in anima...

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Bibliographic Details
Main Authors: Sara F Hansson, Alex-Xianghua Zhou, Paulina Vachet, Jan W Eriksson, Maria J Pereira, Stanko Skrtic, Helen Jongsma Wallin, Anders Ericsson-Dahlstrand, Daniel Karlsson, Andrea Ahnmark, Maria Sörhede Winzell, Maria Chiara Magnone, Pia Davidsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5922551?pdf=render

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http://europepmc.org/articles/PMC5922551?pdf=render

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