Insulin-like growth factor-1 inhibits the apoptosis of rat gastric smooth muscle cells cultured under high glucose condition through PI3K-Akt-PKC-Ca2+ pathway

Insulin-like growth factor-1 inhibits the apoptosis of rat gastric smooth muscle cells cultured under high glucose condition through PI3K-Akt-PKC-Ca2+ pathway

This study investigated the effect of insulin-like growth factor 1 (IGF-1) on rat gastric smooth muscle cell apoptosis under high glucose conditions, and explored the involvement of the PI3K-Akt-PKC-Ca2+ pathway. Rat gastric smooth muscle cells were cultured in vitro under normal and high glucose co...

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Bibliographic Details
Main Authors: Xue-Sen Fang, Mo-Han Zhang, Xiang-Zi Zhang, Jun-Yu Guo, Zheng Jin
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
insulin-like growth factor-1
smooth muscle cells
high glucose
cell apoptosis
pi3k-akt pathway
pkc activity
ca2+ concentration
Online Access:http://dx.doi.org/10.1080/13102818.2019.1585206

Internet

http://dx.doi.org/10.1080/13102818.2019.1585206

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