<i>piggy</i>Bac Transposon-Based Immortalization of Human Deciduous Tooth Dental Pulp Cells with Multipotency and Non-Tumorigenic Potential

<i>piggy</i>Bac Transposon-Based Immortalization of Human Deciduous Tooth Dental Pulp Cells with Multipotency and Non-Tumorigenic Potential

We aimed to immortalize primarily isolated human deciduous tooth-derived dental pulp cells (HDDPCs) by transfection with <i>piggy</i>Bac (PB)-based transposon vectors carrying <i>E7</i> from human papilloma virus 16 or complementary DNA (cDNA) encoding human telomerase revers...

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Bibliographic Details
Main Authors: Emi Inada, Issei Saitoh, Naoko Kubota, Yoko Iwase, Yuki Kiyokawa, Shinji Shibasaki, Hirofumi Noguchi, Youichi Yamasaki, Masahiro Sato
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
immortalization
telomerase reverse transcriptase
e7
human deciduous tooth-derived dental pulp cell
<i>piggy</i>bac
multi-differentiation potential
tumorigenicity
stemness factor
alkaline phosphatase
Online Access:https://www.mdpi.com/1422-0067/20/19/4904

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https://www.mdpi.com/1422-0067/20/19/4904

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