Clinical application of a lung cancer organoid (tumoroid) culture system

Abstract Despite high expectations for lung tumoroids, they have not been applied in the clinic due to the difficulty of their long-term culture. Here, however, using AO (airway organoid) media developed by the Clevers laboratory, we succeeded in generating 3 lung tumoroid lines for long-term cultur...

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Main Authors: Etsuko Yokota, Miki Iwai, Takuro Yukawa, Masakazu Yoshida, Yoshio Naomoto, Minoru Haisa, Yasumasa Monobe, Nagio Takigawa, Minzhe Guo, Yutaka Maeda, Takuya Fukazawa, Tomoki Yamatsuji
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00166-3