Implications of Inter-Individual Differences in Clopidogrel Metabolism, with Focus on Pharmacogenetics

Increasing evidence for the role of pharmacogenetics in treatment resistance to the antiplatelet agent clopidogrel has been gained during the last years. Apart from CYP2C19 genetic polymorphisms, nongenetic factors, particularly drug-drug interactions, age and other clinical characteristics influenc...

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Bibliographic Details
Main Authors: Arzu Gunes, Marja-Liisa Dahl
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/3/4/782/