Chorioamnionitis Induces a Specific Signature of Placental ABC Transporters Associated with an Increase of miR-331-5p in the Human Preterm Placenta

Chorioamnionitis Induces a Specific Signature of Placental ABC Transporters Associated with an Increase of miR-331-5p in the Human Preterm Placenta

Background/Aims: The ATP-binding cassette (ABC) transporters mediate drug biodisposition and immunological responses in the placental barrier. In vitro infective challenges alter expression of specific placental ABC transporters. We hypothesized that chorioamnionitis induces a distinct pattern of AB...

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Bibliographic Details
Main Authors: Guinever Eustaquio do Imperio, Enrrico Bloise, Mohsen Javam, Phetcharawan Lye, Andrea Constantinof, Caroline Dunk, Fernando Marcos dos Reis, Stephen James Lye, William Gibb, Tania M. Ortiga-Carvalho, Stephen Giles Matthews
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Placenta
Chorioamnionitis
Preterm delivery
ABC transporters
P-glycoprotein (P-gp)
Breast cancer resistance protein (BCRP).
Online Access:https://www.karger.com/Article/FullText/487100

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https://www.karger.com/Article/FullText/487100

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