Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis

Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis

We previously reported that i) a Western diet increased levels of unsaturated lysophosphatidic acid (LPA) in small intestine and plasma of LDL receptor null (LDLR−/−) mice, and ii) supplementing standard mouse chow with unsaturated (but not saturated) LPA produced dyslipidemia and inflammation. Here...

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Bibliographic Details
Main Authors: Mohamad Navab, Arnab Chattopadhyay, Greg Hough, David Meriwether, Spencer I. Fogelman, Alan C. Wagner, Victor Grijalva, Feng Su, G.M. Anantharamaiah, Lin H. Hwang, Kym F. Faull, Srinivasa T. Reddy, Alan M. Fogelman
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Journal of Lipid Research
Subjects:
lysophosphatidylcholine
6F peptide
apolipoprotein A-I mimetic peptides
genetically engineered tomato plants
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520355681

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http://www.sciencedirect.com/science/article/pii/S0022227520355681

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