The participation of RANK, RANKL and OPG in tumor osteolysis

The participation of RANK, RANKL and OPG in tumor osteolysis

It was recently shown that physiological bone remodeling depends on the dynamic balance of two cytokines that are predominantly secreted by osteoblasts. RANKL promotes the differentiation of osteoclastic precursors and the activation of osteoclasts, whereas osteoprotegerin (OPG) inhibits RANKL actio...

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Bibliographic Details
Main Authors: Marcin Stanisławowski, Zbigniew Kmieć
Format: Article
Language:English
Published: Index Copernicus International S.A. 2009-05-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
RANK
RANKL
OPG
Osteoclasts
Osteoblasts
tumor osteolysis
Online Access:http://journals.indexcopernicus.com/fulltxt.php?ICID=885840

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