The participation of RANK, RANKL and OPG in tumor osteolysis
It was recently shown that physiological bone remodeling depends on the dynamic balance of two cytokines that are predominantly secreted by osteoblasts. RANKL promotes the differentiation of osteoclastic precursors and the activation of osteoclasts, whereas osteoprotegerin (OPG) inhibits RANKL actio...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Index Copernicus International S.A.
2009-05-01
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Series: | Postępy Higieny i Medycyny Doświadczalnej |
Subjects: | |
Online Access: | http://journals.indexcopernicus.com/fulltxt.php?ICID=885840 |