Lymphoid aggregates that resemble tertiary lymphoid organs define a specific pathological subset in metal-on-metal hip replacements.

Aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL) has been used to describe the histological lesion associated with metal-on-metal (M-M) bearings. We tested the hypothesis that the lymphoid aggregates, associated with ALVAL lesions resemble tertiary lymphoid organs (TLOs). Histopatho...

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Bibliographic Details
Main Authors: Saloni Mittal, Matthew Revell, Francesca Barone, Debbie L Hardie, Gulraj S Matharu, Alison J Davenport, Richard A Martin, Melissa Grant, Frederick Mosselmans, Paul Pynsent, Vaiyapuri P Sumathi, Owen Addison, Peter A Revell, Christopher D Buckley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23723985/pdf/?tool=EBI