Synergistic killing effects of homoharringtonine and arsenic trioxide on acute myeloid leukemia stem cells and the underlying mechanisms

Synergistic killing effects of homoharringtonine and arsenic trioxide on acute myeloid leukemia stem cells and the underlying mechanisms

Abstract Background At present, it is generally believed that leukemia stem cells are the source of AML, so the killing of leukemia stem cells has become important. Previous studies have suggested that HHT combined with ATO can synergistically kill U937 cells, and HHT has also demonstrated the abili...

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Bibliographic Details
Main Authors: Ming Tan, Qian Zhang, Xiaohong Yuan, Yuanzhong Chen, Yong Wu
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Homoharringtonine
Arsenic trioxide
LSC
Notch
Xenograft leukemia model
Online Access:http://link.springer.com/article/10.1186/s13046-019-1295-8

Internet

http://link.springer.com/article/10.1186/s13046-019-1295-8

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