The dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3G

<p>Abstract</p> <p>Background</p> <p>The HIV-1 accessory protein known as viral infectivity factor or Vif binds to the host defence factor human APOBEC3G (hA3G) and prevents its assembly with viral particles and mediates its elimination through ubiquitination and degrad...

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Bibliographic Details
Main Authors: Presnyak Vlad, Miller James H, Smith Harold C
Format: Article
Language:English
Published: BMC 2007-11-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/4/1/81