Extraction of BoNT/A, /B, /E, and /F with a single, high affinity monoclonal antibody for detection of botulinum neurotoxin by Endopep-MS.

Botulinum neurotoxins (BoNTs) are extremely potent toxins that are capable of causing respiratory failure leading to long-term intensive care or death. The best treatment for botulism includes serotype-specific antitoxins, which are most effective when administered early in the course of the intoxic...

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Bibliographic Details
Main Authors: Suzanne R Kalb, Consuelo Garcia-Rodriguez, Jianlong Lou, Jakub Baudys, Theresa J Smith, James D Marks, Leonard A Smith, James L Pirkle, John R Barr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2923190?pdf=render