Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

The conserved role of Notch signaling in controlling intestinal cell fate specification and homeostasis has been extensively studied. Nevertheless, the precise identity of the cells in which Notch signaling is active and the role of different Notch receptor paralogues in the intestine remain ambiguo...

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Bibliographic Details
Main Authors: Silvia Fre, Edouard Hannezo, Sanja Sale, Mathilde Huyghe, Daniel Lafkas, Holger Kissel, Angeliki Louvi, Jeffrey Greve, Daniel Louvard, Spyros Artavanis-Tsakonas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3185035?pdf=render