RNAScope in situ Hybridization as a Novel Technique for the Assessment of c-KIT mRNA Expression in Canine Mast Cell Tumor

RNAScope in situ Hybridization as a Novel Technique for the Assessment of c-KIT mRNA Expression in Canine Mast Cell Tumor

RNA is considered as an indicator of the dynamic genetic expression changes in a cell. RNAScope is a commercially available in situ hybridization assay for the detection of RNA in formalin-fixed paraffin-embedded tissue. In this work, we describe the use of RNAScope as a sensitive and specific metho...

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Bibliographic Details
Main Authors: Davide De Biase, Francesco Prisco, Giuseppe Piegari, Arianna Ilsami, Ilaria d'Aquino, Valeria Baldassarre, Federica Zito Marino, Renato Franco, Serenella Papparella, Orlando Paciello
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Veterinary Science
Subjects:
RNAscope
c-kit
mRNA
immunohistochemistry
canine mast cell tumor
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.591961/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.591961/full

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