Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma

Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma

Malignant pleural mesothelioma (MPM) is a lethal cancer with limited treatment options. No targeted therapy has emerged yet. Here, we performed an integrated molecular characterization of patient tumors in the TCGA dataset, and discovered that endoplasmic reticulum (ER) stress and the adaptive unfol...

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Bibliographic Details
Main Authors: Duo Xu, Haitang Yang, Zhang Yang, Sabina Berezowska, Yanyun Gao, Shun-Qing Liang, Thomas M. Marti, Sean R. R. Hall, Patrick Dorn, Gregor J. Kocher, Ralph A. Schmid, Ren-Wang Peng
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
malignant pleural mesothelioma (mpm)
endoplasmic reticulum (er) stress
unfolded protein response (upr)
ha15
autophagy
Online Access:https://www.mdpi.com/2072-6694/11/10/1502

Internet

https://www.mdpi.com/2072-6694/11/10/1502

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