Impaired CD8 T cell antiviral immunity following acute spinal cord injury

Abstract Background Spinal cord injury (SCI) disrupts essential neuroimmune communication, leading to severe immune depression. Previous studies confirmed immune dysfunction in mice with chronic SCI and following high thoracic level injury where sympathetic innervation of the spleen is disrupted. He...

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Bibliographic Details
Main Authors: Diana M. Norden, John R. Bethea, Jiu Jiang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-018-1191-8