Acid-Sensing Ion Channels and Pain

Pathophysiological conditions such as inflammation, ischemia, infection and tissue injury can all evoke pain, and each is accompanied by local acidosis. Acid sensing ion channels (ASICs) are proton-gated cation channels expressed in both central and peripheral nervous systems. Increasing evidence su...

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Bibliographic Details
Main Authors: Qihai Gu, Lu-Yuan Lee
Format: Article
Language:English
Published: MDPI AG 2010-05-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/3/5/1411/