Acid-Sensing Ion Channels and Pain
Pathophysiological conditions such as inflammation, ischemia, infection and tissue injury can all evoke pain, and each is accompanied by local acidosis. Acid sensing ion channels (ASICs) are proton-gated cation channels expressed in both central and peripheral nervous systems. Increasing evidence su...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-05-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8247/3/5/1411/ |