Generation and functional characterization of the anti-transferrin receptor single-chain antibody-GAL4 (TfRscFv-GAL4) fusion protein

<p>Abstract</p> <p>Background</p> <p>The development of vectors for cell-specific gene delivery is a major goal of gene therapeutic strategies. Transferrin receptor (TfR) is an endocytic receptor and identified as tumor relative specific due to its overexpression on mos...

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Bibliographic Details
Main Authors: Ye Qing, Hu Heyu, Wang Zhihua, Lu Tong, Hu Zhiquan, Zeng Xing, Zhang Shu, Liu Jing, Lei Ping, Wang Cong-Yi, Ye Zhangqun, Shen Guanxin
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/12/91