To Develop With Or Without The Prion Protein
The deletion of the cellular form of the prion protein (PrPC) in mouse, goat and cattle has no drastic phenotypic consequence. This stands in apparent contradiction with PrPC quasi- ubiquitous expression and conserved primary and tertiary structures in mammals, and its pivotal role in neurodegenerat...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-10-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00058/full |