An Effective Method to Measure Disease Similarity Using Gene and Phenotype Associations

Motivation: In order to create controlled vocabularies for shared use in different biomedical domains, a large number of biomedical ontologies such as Disease Ontology (DO) and Human Phenotype Ontology (HPO), etc., are created in the bioinformatics community. Quantitative measures of the association...

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Bibliographic Details
Main Authors: Shuhui Su, Lei Zhang, Jian Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00466/full