CERA Attenuates Kidney Fibrogenesis in the db/db Mouse by Influencing the Renal Myofibroblast Generation

CERA Attenuates Kidney Fibrogenesis in the db/db Mouse by Influencing the Renal Myofibroblast Generation

Tubulointerstitial fibrosis (TIF) is a pivotal pathophysiological process in patients with diabetic nephropathy (DN). Multiple profibrotic factors and cell types, including transforming growth factor beta 1 (TGF-β1) and interstitial myofibroblasts, respectively, are responsible for the accumulation...

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Bibliographic Details
Main Authors: Christin Fischer, Natalie Deininger, Gunter Wolf, Ivonne Loeffler
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Journal of Clinical Medicine
Subjects:
diabetic nephropathy
DN
erythropoietin
EPO
CERA
tubulointerstitial fibrosis
TIF
myofibroblast
type 2 diabetes
db/db mouse
Online Access:http://www.mdpi.com/2077-0383/7/2/15

Internet

http://www.mdpi.com/2077-0383/7/2/15

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