Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis

Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis

Abstract Background Acute chorioamnionitis (aCA), inflammation of the placenta and fetal membranes, is a frequently reported lesion in preterm deliveries. Genetic variants in innate immune system genes such as Interleukin-6 (IL6) may contribute to the placenta’s inflammatory response, thus predispos...

Full description

Bibliographic Details
Main Authors: Chaini Konwar, Giulia F. Del Gobbo, Jefferson Terry, Wendy P. Robinson
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Medical Genetics
Subjects:
Placenta
Chorioamnionitis
SNP
Interleukin-6
DNA methylation
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12881-019-0768-0

Internet

http://link.springer.com/article/10.1186/s12881-019-0768-0

Similar Items