Treatment of paroxysmal nocturnal hemoglobinuria

<p>Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life‑threatening clonal hematological disorder caused by an acquired mutation in the phosphatidylinositol glucan (PIG)-A gene. PNH is characterized by chronic intravascular hemolysis, marrow failure, thrombophilia and other severe clinica...

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Bibliographic Details
Main Authors: I. A. Lisukov, A. D. Kulagin, B. V. Afanasyev
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Onkogematologiâ
Subjects:
Online Access:http://oncohematology.abvpress.ru/index.php/ongm/article/view/54