The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism

The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism

Energy substrate imbalance is a major cause of cardiac dysfunction. Vitamin D/vitamin D receptor (VD/VDR) deficiency is involved in the pathogenesis of various cardiac diseases; however, the exact underlying mechanism remains unclear. The aim of this study was to investigate whether vitamin D modula...

Full description

Bibliographic Details
Main Authors: Jingxin Yang, Yalin Zhang, Yiming Pan, Can Sun, Zuwang Liu, Ning Liu, Yu Fu, Xiaofeng Li, Ye Li, Juan Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Vitamin D
fatty acid metabolism
Sirtuin 3
mitochondria
cardiac function
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.627135/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.627135/full

Similar Items