HTLV-1 and Adult T-Cell Leukemia: Insights into Viral Transformation of Cells 30 Years After Virus Discovery

Human T-cell leukemia virus type 1 (HTLV-1), the etiological agent of adult T-cell leukemia, was the first human retrovirus to be isolated. It is now the 30th anniversary of the initial discovery of HTLV-1. This review discusses recent insights into the role of the HTLV-1 Tax oncoprotein in cellular...

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Bibliographic Details
Main Author: Kuan-Teh Jeang
Format: Article
Language:English
Published: Elsevier 2010-10-01
Series:Journal of the Formosan Medical Association
Subjects:
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S092966461060112X