STIM1-mediated bidirectional regulation of Ca2+ entry through Voltage-Gated Calcium Channels (VGCC) and Calcium-Release Activated Channels (CRAC)

The spatial and temporal regulation of cellular calcium signals is modulated via two main Ca2+ entry routes. Voltage-gated Ca2+ channels (VGCC) and Ca2+-release activated channels (CRAC) enable Ca2+ flow into electrically excitable and non-excitable cells, respectively. VGCC are well characterized t...

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Bibliographic Details
Main Authors: Osama F. Harraz, Christophe eAltier
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00043/full