Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable stage III colorectal adenocarcinomas.

Although the prognostic value of p53 abnormalities in Stage III microsatellite stable (MSS) colorectal cancers (CRCs) is known, the gene expression profiles specific to the p53 status in the MSS background are not known. Therefore, the current investigation has focused on identification and validati...

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Main Authors: Venkat R Katkoori, Chandrakumar Shanmugam, Xu Jia, Swaroop P Vitta, Meenakshi Sthanam, Tom Callens, Ludwine Messiaen, Dongquan Chen, Bin Zhang, Harvey L Bumpers, Temesgen Samuel, Upender Manne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22276141/pdf/?tool=EBI