Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis

Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis

In cancer cells, a vital cellular process during metastasis is the transformation of epithelial cells towards motile mesenchymal cells called the epithelial to mesenchymal transition (EMT). The cytoskeleton is an active network of three intracellular filaments: actin cytoskeleton, microtubules, and...

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Bibliographic Details
Main Authors: Arpita Datta, Shuo Deng, Vennila Gopal, Kenneth Chun-Hong Yap, Clarissa Esmeralda Halim, Mun Leng Lye, Mei Shan Ong, Tuan Zea Tan, Gautam Sethi, Shing Chuan Hooi, Alan Prem Kumar, Celestial T. Yap
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
actin cytoskeleton
epithelial to mesenchymal transition
metastasis
multidrug resistance
Online Access:https://www.mdpi.com/2072-6694/13/8/1882

Internet

https://www.mdpi.com/2072-6694/13/8/1882

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