Bioinformatics prediction and experimental validation of VH antibody fragment interacting with Neisseria meningitidis factor H binding protein

Bioinformatics prediction and experimental validation of VH antibody fragment interacting with Neisseria meningitidis factor H binding protein

<em><strong>Objective(s):</strong></em> We previously conducted an in silico research on the interactions between the ribosome display-selected single chain variable fragment (scFv) and factor H binding protein (fHbp) of Neisseria meningitidis. We found that heavy chain varia...

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Bibliographic Details
Main Authors: Hediyeh Rafighdoust, Shahrzad Ahangarzadeh, Fatemeh Yarian, Ramezan Ali Taheri, Arezou Lari, Mojgan Bandehpour, Mona Salahshoor Dahr
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
cloning
heavy chain variable
modeling
molecular docking
surface plasmon resonance
Online Access:http://ijbms.mums.ac.ir/article_15834_fb1a1b340c2fd8fefbadbda848d08ffd.pdf

Internet

http://ijbms.mums.ac.ir/article_15834_fb1a1b340c2fd8fefbadbda848d08ffd.pdf

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