Novel (−)-goniofufurone mimics: Synthesis, antiproliferative activity and SAR analysis

Divergent syntheses of novel (–)-goniofufurone mimics with an alkoxymethyl group as the side chain have been accomplished from D-glucose in nine synthetic steps and in overall yields 6.7–8.7 %. Their in vitro antiproliferative activity was evaluated against eight human tumour cell lines as well as a...

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Bibliographic Details
Main Authors: Srećo-Zelenović Bojana, Kekezović Slađana, Popsavin Mirjana, Kojić Vesna, Benedeković Goran, Popsavin Velimir
Format: Article
Language:English
Published: Serbian Chemical Society 2019-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2019/0352-51391900104S.pdf